M&T Bank is a regional bank holding company providing retail and commercial banking services primarily across the northeastern United States, including checking and savings accounts, commercial loans and mortgage lending. As a regional bank, its profitability depends largely on the spread between interest earned on loans and interest paid on deposits, a relationship that's sensitive to Federal Reserve interest rate policy and the shape of the yield curve. M&T has grown partly through acquisitions of other regional banks over the years, expanding its branch network and deposit base across its northeastern footprint. The bank's loan portfolio spans commercial real estate, commercial and industrial loans, and residential mortgages, giving it exposure to regional economic conditions and property markets across the communities it serves.